Laser Stimulation of Nerve Cells in Aplysia

  title={Laser Stimulation of Nerve Cells in Aplysia},
  author={R. Fork},
  pages={907 - 908}
  • R. Fork
  • Published 1971
  • Biology, Medicine
  • Science
Laser radiation at 488 nanometers selectively stimulates neurons in the abdominal ganglion of the marine mollusk Aplysia californica. The laser radiation can be scanned over the surface of the ganglion and can be effectively utilized in mapping cellular interconnections. The laser appears to cause these changes through some mechanism other than damage. 

Topics from this paper

Effects of Argon laser irradiation on polar excitations in frog sciatic nerve
It is shown that low-power laser irradiation can influence ionic channels of the nerve membrane using the law of polar excitation in isolated frog sciatic nerve, and this results in down-regulation in the activity of these channels in the nervous system. Expand
Green laser light (532nm) activates a chloride current in the C1 neuron of Helix aspersa
Detailed experiments on the C1 neuron showed that inhibition results from a selective increase in transmembrane Cl(-) ion conductance, and experiments with calcium-sensitive microelectrodes suggest that the response does not result from an increase in [Ca(2+)](i). Expand
Laser stimulation of the auditory nerve
In contrast to electric stimulation, optical radiation can provide spatially selective neural stimulation without tissue contact, and this work has shown that this approach to neural stimulation is feasible and effective in both the animal and human studies. Expand
Identification of presynaptic neurons by laser photostimulation.
An optical method involving the use of a laser and a novel fluorescent dye as a photostimulation probe has been developed to identify presynaptic neurons in a large ensemble of cells, speeding up the elucidation of neuronal networks. Expand
Multiphoton stimulation of neurons.
The combination of multiphoton stimulation and optical probing could enable systematic analysis of circuits and produce sustained depolarization, insensitive to sodium channel blockers yet sensitive to antioxidants. Expand
Effect of low power 655 nm diode laser irradiation on the neuromuscular junctions of the mouse diaphragm
Low level laser therapy (LLLT) in specific wavelengths and fluence maintains the electrophysiological activity of injured peripheral nerve in rats, preventing scar formation (at injury site) as wellExpand
Effects of Helium-Neon Laser Irradiation and Local Anesthetics on Potassium Channels in Pond Snail Neurons
Intracellular dialysis and membrane voltage clamping were used to show that He-Ne laser irradiation of a pond snail neuron increases the amplitude of the potential-dependent slow potassium current, while a dose of 0.7⋅10−3 J decreases this current. Expand
Optical Stimulation of Peripheral Nerves In Vivo
A novel method of stimulation of neural tissue using pulsed, low-energy laser light is presented. Optical stimulation elicits nerve and muscle action potentials similar to responses obtained withExpand
Acetylcholine releasing effect of laser irradiation on Auerbach's plexus in guinea-pig ileum
An increased acetylcholine release could be produced by ruby laser from the Auerbach plexus of the guinea-pig ileum.
Infrared Neural Modulation: Photothermal Effects on Cortex Neurons Using Infrared Laser Heating
It would be of great value to have a precise and non-damaging neuromodulation technique in the field of basic neuroscience research and for clinical treatment of neurological diseases. Infrared neuExpand


Direct and common connections among identified neurons in Aplysia.
Confocal multimode resonator for millimeter through optical wavelength masers
Multimode resonators of high quality factor will very likely play a significant role in the development of devices, such as the maser, which operate in the millimeter through optical wavelengthExpand