Laser Fabrication of 3D Gelatin Scaffolds for the Generation of Bioartificial Tissues

  title={Laser Fabrication of 3D Gelatin Scaffolds for the Generation of Bioartificial Tissues},
  author={Aleksandr Ovsianikov and Andrea Deiwick and Sandra Van Vlierberghe and Michael Pflaum and Mathias Wilhelmi and Peter Dubruel and Boris N. Chichkov},
In the present work, the two-photon polymerization (2PP) technique was applied to develop precisely defined biodegradable 3D tissue engineering scaffolds. The scaffolds were fabricated via photopolymerization of gelatin modified with methacrylamide moieties. The results indicate that the gelatin derivative (GelMod) preserves its enzymatic degradation capability after photopolymerization. In addition, the developed scaffolds using 2PP support primary adipose-derived stem cell (ASC) adhesion… CONTINUE READING

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