Larynx vs. esophagus as reflexogenic sites for acid-induced bronchoconstriction in dogs.

@article{Ishikawa1999LarynxVE,
  title={Larynx vs. esophagus as reflexogenic sites for acid-induced bronchoconstriction in dogs.},
  author={Tomohiro Ishikawa and Shingo Sekizawa and F Sant'ambrogio and G Sant'ambrogio},
  journal={Journal of applied physiology},
  year={1999},
  volume={86 4},
  pages={1226-30}
}
Bronchoconstriction in asthmatic patients is frequently associated with gastroesophageal reflux. However, it is still unclear whether bronchoconstriction originates from the esophagus or from aspiration of the refluxate into the larynx and larger airway. We compared the effect of repeated esophageal and laryngeal instillations of HCl-pepsin (pH 1.0) on… CONTINUE READING