Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis

@inproceedings{Andersen2017LaryngealRP,
  title={Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis},
  author={Tiina Andersen and Astrid Sandnes and Anne Kristine Brekka and Magnus Hilland and Hege Synn{\o}ve Havstad Clemm and Ove Fondenes and Ole-Bj{\o}rn Tysnes and Jan Heimdal and Thomas Halvorsen and Maria Volls{\ae}ter and Ola Drange R{\o}ksund},
  booktitle={Thorax},
  year={2017}
}
BACKGROUND Most patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical insufflation-exsufflation (MI-E) in order to improve cough. This method often fails in ALS with bulbar involvement, allegedly due to upper-airway malfunction. We have studied this phenomenon in detail with laryngoscopy to unravel information that could lead to better treatment. METHODS We conducted a cross-sectional study of 20 patients with ALS and 20 healthy age-matched and sex-matched volunteers… CONTINUE READING
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