Large volume donor plasmapheresis in inherited thrombophilia implicated in arterial thrombosis.

@article{Ovali2003LargeVD,
  title={Large volume donor plasmapheresis in inherited thrombophilia implicated in arterial thrombosis.},
  author={Erc{\"u}ment Ovali and Siret Ratip and Mehmet Ozmenoğlu and Suleyman Sami Karti and Fahri Uçar and Kubilay Ukinç and Mustafa Yilmaz and Polat Koşucu},
  journal={Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis},
  year={2003},
  volume={28 3},
  pages={201-6}
}
BACKGROUND Life-threatening complications following apheresis are rare, and include venous thrombosis. Arterial thrombosis following apheresis has not been reported. CASE REPORT A 48 year old donor had cerebral infarction following large volume plasma donation. The outcome was fatal. He was found to be heterozygous for both methylene tetrahydrofolate reductase (MTHFR) 677C-T mutation and Prothrombin 20210G-A allele. CONCLUSION This case suggests that large volume plasma donation may trigger… CONTINUE READING
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