Large-scale synthesis of peptides.

@article{Andersson2000LargescaleSO,
  title={Large-scale synthesis of peptides.},
  author={Lars O. Andersson and Lars Blomberg and Martin Flegel and Ludek Lepsa and Bj{\"o}rn E. Nilsson and Michael S. Verlander},
  journal={Biopolymers},
  year={2000},
  volume={55 3},
  pages={227-50}
}
Recent advances in the areas of formulation and delivery have rekindled the interest of the pharmaceutical community in peptides as drug candidates, which, in turn, has provided a challenge to the peptide industry to develop efficient methods for the manufacture of relatively complex peptides on scales of up to metric tons per year. This article focuses on chemical synthesis approaches for peptides, and presents an overview of the methods available and in use currently, together with a… CONTINUE READING