Large-scale synthesis of bioinert tantalum oxide nanoparticles for X-ray computed tomography imaging and bimodal image-guided sentinel lymph node mapping.

@article{Oh2011LargescaleSO,
  title={Large-scale synthesis of bioinert tantalum oxide nanoparticles for X-ray computed tomography imaging and bimodal image-guided sentinel lymph node mapping.},
  author={Myoung Hwan Oh and Nohyun Lee and Hyoungsu Kim and Seung Pyo Park and Yuanzhe Piao and Jisoo Lee and Samuel Woojoo Jun and Woo Kyung Moon and Seung Hong Choi and Taeghwan Hyeon},
  journal={Journal of the American Chemical Society},
  year={2011},
  volume={133 14},
  pages={5508-15}
}
Ever since Au nanoparticles were developed as X-ray contrast agents, researchers have actively sought alternative nanoparticle-based imaging probes that are not only inexpensive but also safe for clinical use. Herein, we demonstrate that bioinert tantalum oxide nanoparticles are suitable nanoprobes for high-performance X-ray computed tomography (CT) imaging while simultaneously being cost-effective and meeting the criteria as a biomedical platform. Uniformly sized tantalum oxide nanoparticles… CONTINUE READING