Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct.

@article{Yu2008LargescaleQL,
  title={Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct.},
  author={Ming-Jiun Yu and Trairak Pisitkun and Guanghui Wang and Juan Francisco Aranda and Patricia A Gonzales and Dmitry Tchapyjnikov and Rong-Fong Shen and Miguel A. Alonso and Mark A. Knepper},
  journal={American journal of physiology. Cell physiology},
  year={2008},
  volume={295 3},
  pages={C661-78}
}
In the renal collecting duct, vasopressin controls transport of water and solutes via regulation of membrane transporters such as aquaporin-2 (AQP2) and the epithelial urea transporter UT-A. To discover proteins potentially involved in vasopressin action in rat kidney collecting ducts, we enriched membrane "raft" proteins by harvesting detergent-resistant… CONTINUE READING