Large-scale prediction of long non-coding RNA functions in a coding–non-coding gene co-expression network

@inproceedings{Liao2011LargescalePO,
  title={Large-scale prediction of long non-coding RNA functions in a coding–non-coding gene co-expression network},
  author={Qi Liao and Changning Liu and Xiongying Yuan and Shuli Kang and Ruoyu Miao and Hui Xiao and Guoguang Zhao and Haitao Luo and Dechao Bu and Haitao Zhao and Geir Skogerb\o and Zhongdao Wu and Yi Zhao},
  booktitle={Nucleic acids research},
  year={2011}
}
Although accumulating evidence has provided insight into the various functions of long-non-coding RNAs (lncRNAs), the exact functions of the majority of such transcripts are still unknown. Here, we report the first computational annotation of lncRNA functions based on public microarray expression profiles. A coding-non-coding gene co-expression (CNC) network was constructed from re-annotated Affymetrix Mouse Genome Array data. Probable functions for altogether 340 lncRNAs were predicted based… CONTINUE READING
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