Large-scale neuronal network dysfunction in multiple sclerosis?

@article{Enzinger2012LargescaleNN,
  title={Large-scale neuronal network dysfunction in multiple sclerosis?},
  author={Christian Enzinger and John DeLuca},
  journal={Neurology},
  year={2012},
  volume={79},
  pages={1416 - 1417}
}
After decades of intensive research, the pathogenesis of multiple sclerosis (MS) remains enigmatic. Neuroimaging has fueled the discovery of hitherto underestimated or unknown pathophysiologic aspects of MS, revealing, for example, widespread damage to normal-appearing white matter and cortical and 
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