Large-scale neural ensemble recording in the brains of freely behaving mice

  title={Large-scale neural ensemble recording in the brains of freely behaving mice},
  author={L. Lin and Guifen Chen and Kun Xie and K. Zaia and J. Tsien},
  journal={Journal of Neuroscience Methods},
  • L. Lin, Guifen Chen, +2 authors J. Tsien
  • Published 2006
  • Psychology, Medicine
  • Journal of Neuroscience Methods
  • With the availability of sophisticated genetic techniques, the mouse is a valuable mammalian model to study the molecular and cellular basis of cognitive behaviors. However, the small size of mice makes it difficult for a systematic investigation of activity patterns of neural networks in vivo. Here we report the development and construction of a high-density ensemble recording array with up to 128-recording channels that can be formatted as single electrodes, stereotrodes, or tetrodes. This… CONTINUE READING
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