Large-scale identification of novel mitosis-specific phosphoproteins.

@article{Xiang2008LargescaleIO,
  title={Large-scale identification of novel mitosis-specific phosphoproteins.},
  author={Ma Xiang and Cao Xue and Li Huicai and Liu Jin and Li Hong and He Dacheng},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1784 6},
  pages={882-90}
}
Systematic identification of phosphoproteins is essential for understanding cellular signalling pathways since phosphorylation plays important roles in cellular regulation. Monoclonal antibody MPM-2 recognizes a discrete set of mitosis-specific phosphoproteins and constitutes a specific tool to investigate the significance of phosphorylation in cell cycle. However, due to the difficulties in identifying antigens revealed on immunoblot membrane, only minority of MPM-2 antigens have been… CONTINUE READING

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