Large-scale finite element analysis of the beating heart.

  title={Large-scale finite element analysis of the beating heart.},
  author={Andrew D. McCulloch and Lewis K. Waldman and J M Rogers and Julius M. Guccione},
  journal={Critical reviews in biomedical engineering},
  volume={20 5-6},
The regional mechanics of the beating heart are directly related to factors such as ventricular pumping performance, coronary blood flow, myocardial energetics and oxygen consumption, vulnerability to ischemia and injury, hypertrophy and remodeling, and arrhythmogenesis. Important characteristics include: the complex three-dimensional geometry and fibrous architecture; the nonlinear, nonhomogeneous, anisotropic material properties of the myocardium; the hierarchical collagen connective tissue… CONTINUE READING

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