Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli


The biochemical and physical factors controlling protein expression level and solubility in vivo remain incompletely characterized. To gain insight into the primary sequence features influencing these outcomes, we performed statistical analyses of results from the high-throughput protein-production pipeline of the Northeast Structural Genomics Consortium… (More)
DOI: 10.1186/2042-5783-1-6


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