Large-scale detection and analysis of RNA editing in grape mtDNA by RNA deep-sequencing

@inproceedings{Picardi2010LargescaleDA,
  title={Large-scale detection and analysis of RNA editing in grape mtDNA by RNA deep-sequencing},
  author={Ernesto Picardi and David Stephen Horner and Matteo De Chiara and Riccardo Schiavon and Giorgio Valle and Graziano Pesole},
  booktitle={Nucleic acids research},
  year={2010}
}
RNA editing is a widespread post-transcriptional molecular phenomenon that can increase proteomic diversity, by modifying the sequence of completely or partially non-functional primary transcripts, through a variety of mechanistically and evolutionarily unrelated pathways. Editing by base substitution has been investigated in both animals and plants. However, conventional strategies based on directed Sanger sequencing are time-consuming and effectively preclude genome wide identification of RNA… CONTINUE READING

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