Large scale data mining approach for gene-specific standardization of microarray gene expression data

@article{Yoon2006LargeSD,
  title={Large scale data mining approach for gene-specific standardization of microarray gene expression data},
  author={Sukjoon Yoon and Young Yang and Jiwon Choi and Jeeweon Seong},
  journal={Bioinformatics},
  year={2006},
  volume={22 23},
  pages={2898-904}
}
MOTIVATION The identification of the change of gene expression in multifactorial diseases, such as breast cancer is a major goal of DNA microarray experiments. Here we present a new data mining strategy to better analyze the marginal difference in gene expression between microarray samples. The idea is based on the notion that the consideration of gene's behavior in a wide variety of experiments can improve the statistical reliability on identifying genes with moderate changes between samples… CONTINUE READING
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