Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing

@article{Wittkop2007LargeSC,
  title={Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing},
  author={Tobias Wittkop and Jan Baumbach and Francisco P. Lobo and Sven Rahmann},
  journal={BMC Bioinformatics},
  year={2007},
  volume={8},
  pages={396 - 396}
}
Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clustering approaches, following different strategies, have been published to attack this problem. Today, new sequencing technologies provide huge amounts of sequence data that has to be efficiently clustered with constant or increased accuracy, at increased speed. We advocate that the model of weighted cluster editing, also known as… CONTINUE READING

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An efficient algorithm for large-scale detection of protein families

  • AJ Enright, SV Dongen, CA Ouzounis
  • Nucleic Acids Res
  • 2002
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