Large scale chromosomal mapping of human microRNA structural clusters

Abstract

MicroRNAs (miRNAs) can group together along the human genome to form stable secondary structures made of several hairpins hosting miRNAs in their stems. The few known examples of such structures are all involved in cancer development. A large scale computational analysis of human chromosomes crossing sequence analysis and deep sequencing data revealed the… (More)
DOI: 10.1093/nar/gkt112

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