Large scale association analysis of novel genetic loci for coronary artery disease.

  title={Large scale association analysis of novel genetic loci for coronary artery disease.},
  author={Nilesh J. Samani and Panagiotis Deloukas and Jeanette Erdmann and Christian Hengstenberg and Kari A Kuulasmaa and Ralph McGinnis and Heribert Schunkert and Nicole Soranzo and John Thompson and Laurence Tiret and Andreas Ziegler},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={29 5},
BACKGROUND Combined analysis of 2 genome-wide association studies in cases enriched for family history recently identified 7 loci (on 1p13.3, 1q41, 2q36.3, 6q25.1, 9p21, 10q11.21, and 15q22.33) that may affect risk of coronary artery disease (CAD). Apart from the 9p21 locus, the other loci await substantive replication. Furthermore, the effect of these loci on CAD risk in a broader range of individuals remains to be determined. METHODS AND RESULTS We undertook association analysis of single… CONTINUE READING
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Genetic Loci for CAD

  • A Helgadottir, G Thorleifsson, +19 authors Samani Borch
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