Large offspring syndrome in cattle and sheep.

@article{Young1998LargeOS,
  title={Large offspring syndrome in cattle and sheep.},
  author={Lorraine E. Young and Kevin D Sinclair and Ian Wilmut},
  journal={Reviews of reproduction},
  year={1998},
  volume={3 3},
  pages={155-63}
}
Bovine and ovine embryos exposed to a variety of unusual environments prior to the blastocyst stage have resulted in the development of unusually large offspring which can also exhibit a number of organ defects. In these animals, the increased incidence of difficult parturition and of fetal and neonatal losses has limited the large-scale use of in vitro embryo production technologies commonly used in humans and other species. Four different situations have been identified that result in the… CONTINUE READING
Highly Influential
This paper has highly influenced a number of papers. REVIEW HIGHLY INFLUENTIAL CITATIONS