Large nested variant of urothelial carcinoma: 23 cases mimicking von Brunn nests and inverted growth pattern of noninvasive papillary urothelial carcinoma.

@article{Cox2011LargeNV,
  title={Large nested variant of urothelial carcinoma: 23 cases mimicking von Brunn nests and inverted growth pattern of noninvasive papillary urothelial carcinoma.},
  author={Roni Michelle Cox and Jonathan I. Epstein},
  journal={The American journal of surgical pathology},
  year={2011},
  volume={35 9},
  pages={1337-42}
}
We describe a rare pattern of urothelial carcinoma (UC) invasion consisting of large, irregular to regular nests, with bland cytology. We prospectively retrieved 23 cases of large nested UC from one of the author's consult files (2001 to 2010). The mean patient age was 63.7 years (39 to 89 y), and 86% were men. There were 18 cases with transurethral resection of the bladder, 2 nephroureterectomy specimens, and 3 radical cystectomy (RCs) specimens. A surface component was present in 19 of 23… CONTINUE READING

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