Large granules in the peripheral blood smear and bone marrow aspirate of a 3-year-old male with lymphadenopathy and fever.

@article{McCoy2014LargeGI,
  title={Large granules in the peripheral blood smear and bone marrow aspirate of a 3-year-old male with lymphadenopathy and fever.},
  author={Morgan H. McCoy and Kelley J Mast and Ryan F Relich and George Girgis and M Reza Nassiri},
  journal={Laboratory medicine},
  year={2014},
  volume={45 3},
  pages={
          244-7
        }
}
A 3-year-old male with oculocutaneous albinism presented with lymphadenopathy and fever. Serological testing revealed Epstein-Barr virus (EBV)-specific immunoglobulin M (IgM) and a diagnosis of infectious mononucleosis was made. A complete blood count and peripheral blood smear demonstrated mild anemia, thrombocytopenia, and neutropenia with leukocytes that contained large azurophilic and eosinophilic granules. Bone marrow examination demonstrated increased hemophagocytic histiocytes along with… CONTINUE READING