Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats

@article{Yang2004LargeDK,
  title={Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats},
  author={Jianjun Yang and Wei-feng Li and Minghua Duan and Zihui Zhou and N T Lin and Zhongyun Wang and Jie Sun and Jian-cheng Xu},
  journal={Inflammation Research},
  year={2004},
  volume={54},
  pages={133-137}
}
Background: Sepsis is associated with the highest risk of progression to acute lung injury or the acute respiratory distress syndrome. Ketamine has been advocated for anesthesia in endotoxemic and other severely ill patients because it is a cardiovascular stimulant. Our study was designed to investigate the effect of ketamine on the endotoxin-induced acute lung injury in vivo. Materials and methods: Adult male Wistar rats were randomly divided into 6 groups: saline controls; rats challenged… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Similar Papers

Loading similar papers…