Large deletion of androsterone UDP-glucuronosyltransferase gene in the inherited deficient strain of Wistar rats.

@article{Homma1992LargeDO,
  title={Large deletion of androsterone UDP-glucuronosyltransferase gene in the inherited deficient strain of Wistar rats.},
  author={Hiroshi Homma and Hiroyuki Kawai and Masaki Kubota and Mizuo Matsui},
  journal={Biochimica et biophysica acta},
  year={1992},
  volume={1138 1},
  pages={34-40}
}
LA Wistar rats have a deficiency of androsterone UDP-glucuronosyltransferase (UDPGT) and are present in Wistar rat colonies around the world. In order to clarify the molecular mechanism of the deficiency, androsterone UDPGT cDNA clone, pGT2 was isolated from rat liver cDNA library and was digested with restriction enzymes to afford three probes for Northern and Southern blot analyses in HA (normal), heterozygous LA and LA Wistar rats. In Northern blot analysis, androsterone UDPGT mRNA was… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…