Large conductance channel in plasma membranes of astrocytic cells is functionally related to mitochondrial VDAC-channels.

@article{Guibert1998LargeCC,
  title={Large conductance channel in plasma membranes of astrocytic cells is functionally related to mitochondrial VDAC-channels.},
  author={Bernard Guibert and Rolf Dermietzel and Detlef Siemen},
  journal={The international journal of biochemistry & cell biology},
  year={1998},
  volume={30 3},
  pages={379-91}
}
Large conductance anion channels with similar electrophysiological characteristics were found in plasma membranes and in outer mitochondrial membranes of various cell types. Although their large conductance and their peculiar voltage dependence point to a close relation, it was questioned whether they belong to the same family. We therefore compared some biochemical features of a plasmalemmal channel with those known from the mitochondrial channel. Current events were recorded from excised… CONTINUE READING

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