Large cohort dose-volume response analysis of parotid gland function after radiotherapy: intensity-modulated versus conventional radiotherapy.

@article{Dijkema2008LargeCD,
  title={Large cohort dose-volume response analysis of parotid gland function after radiotherapy: intensity-modulated versus conventional radiotherapy.},
  author={T. J. Dijkema and Chris H. J. Terhaard and Judith M. Roesink and P{\`e}tra M Braam and Carla H van Gils and Marinus A. Moerland and Cornelis P. J. Raaijmakers},
  journal={International journal of radiation oncology, biology, physics},
  year={2008},
  volume={72 4},
  pages={1101-9}
}
PURPOSE To compare parotid gland dose-volume response relationships in a large cohort of patients treated with intensity-modulated (IMRT) and conventional radiotherapy (CRT). METHODS AND MATERIALS A total of 221 patients (64 treated with IMRT, 157 with CRT) with various head-and-neck malignancies were prospectively evaluated. The distribution of tumor subsites in both groups was unbalanced. Stimulated parotid flow rates were measured before and 6 weeks, 6 months, and 1 year after radiotherapy… CONTINUE READING