Large animal model of ischemic mitral regurgitation.

  title={Large animal model of ischemic mitral regurgitation.},
  author={M R Llaneras and Michael L. Nance and J T Streicher and Jo{\~a}o A. C. Lima and Joseph S. Savino and D K Bogen and R F Deac and Mark B. Ratcliffe and L. Henry Edmunds},
  journal={The Annals of thoracic surgery},
  volume={57 2},
A large animal model of ischemic mitral regurgitation (MR) that resembles the multiple presentations of the human disease was developed in sheep. In 76 sheep hearts, the anatomy of the coronary arterial circulation was determined by observation and polymer casts. Two variations, types A and B, which differed by the vessel that supplied the left ventricular apex, were found. In all hearts, the circumflex coronary artery has three marginal branches and terminates in the posterior descending… CONTINUE READING