Large-Scale Screening of a Targeted Enterococcus faecalis Mutant Library Identifies Envelope Fitness Factors

@inproceedings{RigottierGois2011LargeScaleSO,
  title={Large-Scale Screening of a Targeted Enterococcus faecalis Mutant Library Identifies Envelope Fitness Factors},
  author={Lionel Rigottier-Gois and Adriana Alberti and Armel Houel and Jean-François Taly and Philippe Palcy and Janet Marilyn Manson and Daniela Porto Pinto and Renata C Matos and Laura Carrilero and Natalia Hernandez Montero and Muhammad Shafiq Tariq and Harma A. Karsens and Christian Repp and Andrea Kropec and Aur{\'e}lie Budin-Verneuil and Abdellah Benachour and Nicolas Sauvageot and Alain Bizzini and Michael S. Gilmore and Philippe Bessi{\`e}res and Jan Kok and Johannes Huebner and F{\'a}tima Daniela Teixeira Lopes and B. Gonz{\'a}lez-zorn and Axel Hartke and Pascale Serror},
  booktitle={PloS one},
  year={2011}
}
Spread of antibiotic resistance among bacteria responsible for nosocomial and community-acquired infections urges for novel therapeutic or prophylactic targets and for innovative pathogen-specific antibacterial compounds. Major challenges are posed by opportunistic pathogens belonging to the low GC% gram-positive bacteria. Among those, Enterococcus faecalis is a leading cause of hospital-acquired infections associated with life-threatening issues and increased hospital costs. To better… CONTINUE READING

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