Large-Scale Fractionation of Cigarette Smoke Condensate for Chemical and Biologic Investigations 1

Abstract

Most of the tumorigenicity of CSC for animals can be con centrated in the neutral and acidic fractions. In an early study (19), roughly quantitative results showed that, although the major tumor-initiating activity was concentrated in the carbon tetrachloride eluate from silicic acid chromatography of the neutrals, some activity was found in the hexane… (More)

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