Large Multiple Organism Gene Finding by Collapsed Gibbs Sampling

  title={Large Multiple Organism Gene Finding by Collapsed Gibbs Sampling},
  author={Sourav Chatterji and Lior Pachter},
  journal={Journal of Computational Biology},
The Gibbs sampling method has been widely used for sequence analysis after it was successfully applied to the problem of identifying regulatory motif sequences upstream of genes. Since then, numerous variants of the original idea have emerged: however, in all cases the application has been to finding short motifs in collections of short sequences (typically less than 100 nucleotides long). In this paper, we introduce a Gibbs sampling approach for identifying genes in multiple large genomic… CONTINUE READING
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