Large Mg(2+)-dependent currents are associated with the increased expression of ALR1 in Saccharomyces cerevisiae.

@article{Liu2002LargeMC,
  title={Large Mg(2+)-dependent currents are associated with the increased expression of ALR1 in Saccharomyces cerevisiae.},
  author={Guo Jun Liu and Donald K Martin and Richard C. Gardner and Peter R Ryan},
  journal={FEMS microbiology letters},
  year={2002},
  volume={213 2},
  pages={231-7}
}
Two genes in Saccharomyces cerevisiae, ALR1 and ALR2, encode proteins putatively involved in Mg(2+) uptake. The present study supports this role for ALR1 and provides the first electrophysiological characterisation of this protein. The patch-clamp technique was used to measure whole-cell ion currents in protoplasts prepared from the wild-type strain, the alr1 alr2 double mutant (CM66), and the double mutant over-expressing the ALR1 gene (CM66+ALR1). With 50 mM Mg(2+) in the bathing solution… CONTINUE READING

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