Compressible large-eddy simulations of turbulent flow over a wall-mounted hump with active flow control are performed and compared to previous experiments. We consider a range of Mach numbers from 0.1 to 0.6. Control is applied just before the natural separation point via steady suction and zero-net mass flux oscillatory forcing. Compared with the baseline flow, control shortens the separation bubble length, but is generally found to be less effective at compressible Mach numbers. The LES matches well to the available experimental data for the baseline and steady suction cases. With oscillatory forcing, the LES captures the major flow physics of the large scale shedding of vortical structures, but over-predicts the separation bubble length at low Mach numbers.