Large‐scale production of red blood cells from stem cells: What are the technical challenges ahead?

@article{Rousseau2014LargescalePO,
  title={Large‐scale production of red blood cells from stem cells: What are the technical challenges ahead?},
  author={Guillaume F. Rousseau and M C Giarratana and Luc Douay},
  journal={Biotechnology Journal},
  year={2014},
  volume={9}
}
Blood‐transfusion centers regularly face the challenge of donor blood shortages, especially for rare blood groups. The possibility of producing universal red blood cells from stem cells industrially has become a possible alternative since the successful injection of blood generated in vitro into a human being in 2011. Although there remains many biological and regulatory issues concerning the efficacy and safety of this new product, the major challenge today for future clinical applications is… 

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