Large‐Scale Ex Vivo Generation of Human Red Blood Cells from Cord Blood CD34+ Cells


The ex vivo generation of human red blood cells on a large scale from hematopoietic stem and progenitor cells has been considered as a potential method to overcome blood supply shortages. Here, we report that functional human erythrocytes can be efficiently produced from cord blood (CB) CD34+ cells using a bottle turning device culture system. Safety and… (More)
DOI: 10.1002/sctm.17-0057


7 Figures and Tables