Laparoscopic fluorescence detection of ovarian carcinoma metastases using 5-aminolevulinic acid-induced protoporphyrin IX.

@article{Lning2004LaparoscopicFD,
  title={Laparoscopic fluorescence detection of ovarian carcinoma metastases using 5-aminolevulinic acid-induced protoporphyrin IX.},
  author={Martin C L{\"o}ning and Heyke C Diddens and Wolfgang K{\"u}pker and Klaus Diedrich and Gereon Huettmann},
  journal={Cancer},
  year={2004},
  volume={100 8},
  pages={1650-6}
}
BACKGROUND The aim of the current clinical study was to evaluate the in vivo fluorescence detection of ovarian carcinoma metastases in a second-look laparoscopic procedure after intraperitoneally applied 5-aminolevulinic acid (ALA). METHODS Five hours before laparoscopic surgery, ALA was applied intraperitoneally via short infusion in a concentration of 30 mg/kg bodyweight in a sterile, 1% solution. Application of ALA resulted in the endogenous production of the fluorescent photosensitizer… CONTINUE READING