LapG, required for modulating biofilm formation by Pseudomonas fluorescens Pf0-1, is a calcium-dependent protease.

@article{Boyd2012LapGRF,
  title={LapG, required for modulating biofilm formation by Pseudomonas fluorescens Pf0-1, is a calcium-dependent protease.},
  author={Chelsea D. Boyd and Debashree Chatterjee and Holger Sondermann and George A O'Toole},
  journal={Journal of bacteriology},
  year={2012},
  volume={194 16},
  pages={4406-14}
}
Biofilm formation by Pseudomonas fluorescens Pf0-1 requires the cell surface adhesin LapA. We previously reported that LapG, a periplasmic cysteine protease of P. fluorescens, cleaves the N terminus of LapA, thus releasing this adhesin from the cell surface and resulting in loss of the ability to make a biofilm. The activity of LapG is regulated by the inner membrane-localized cyclic-di-GMP receptor LapD via direct protein-protein interactions. Here we present chelation and metal add-back… CONTINUE READING
17 Citations
44 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Structural basis for c-di-GMP-mediated insideout signaling controlling periplasmic proteolysis

  • MV Navarro
  • PLoS Biol. 9:e1000588
  • 2011
2 Excerpts

Similar Papers

Loading similar papers…