Lantibiotics produced by lactic acid bacteria: structure, function and applications

@article{Twomey2002LantibioticsPB,
  title={Lantibiotics produced by lactic acid bacteria: structure, function and applications},
  author={Denis P. Twomey and R Paul Ross and Maire P. Ryan and Billy Meaney and C. Ray Hill},
  journal={Antonie van Leeuwenhoek},
  year={2002},
  volume={82},
  pages={165-185}
}
Lantibiotics are a diverse group of heavily modified antimicrobial and/or signalling peptides produced by a wide range of bacteria, including a variety of lactic acid bacteria. Based on their diverse structures and mode of action, at least six separate lantibiotic subgroups can be suggested, but all subgroups are characterized by significant post-translational modifications, which include the formation of (β-methyl)lanthionines, among other unusual alterations. These small peptides are produced… CONTINUE READING