Lansoprazole prevents recurrence of erosive reflux esophagitis previously resistant to H2-RA therapy. The Lansoprazole Maintenance Study Group.

@article{Sontag1996LansoprazolePR,
  title={Lansoprazole prevents recurrence of erosive reflux esophagitis previously resistant to H2-RA therapy. The Lansoprazole Maintenance Study Group.},
  author={Stephen J. Sontag and David G. Kogut and Rudolf Fleischmann and Donald R. Campbell and Joel W. Richter and Marian M. Haber},
  journal={The American journal of gastroenterology},
  year={1996},
  volume={91 9},
  pages={
          1758-65
        }
}
OBJECTIVE This randomized, double-blind study was designed to determine whether the proton pump inhibitor lansoprazole could prevent relapse among patients with healed erosive reflux esophagitis that had been resistant to healing with at least 3 months of H2-receptor antagonist therapy. RESULTS By the end of the year, 13% of placebo patients remained healed compared with 67% of lansoprazole 15 mg and 55% of lansoprazole 30 mg patients (p < 0.001 for time to first relapse). All placebo… CONTINUE READING

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Acid-suppressive effects of generic omeprazole: comparison of three brands of generic omeprazole with original omeprazole.

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