Lanosterol synthase-like is involved with differential accumulation of steroidal glycoalkaloids in potato

@article{Kumar2017LanosterolSI,
  title={Lanosterol synthase-like is involved with differential accumulation of steroidal glycoalkaloids in potato},
  author={Akhilesh Kumar and Edna Fogelman and Mira Weissberg and Zachariah Tanami and Richard E Veilleux and Idit Ginzberg},
  journal={Planta},
  year={2017},
  volume={246},
  pages={1189-1202}
}
Main conclusionPhytosterol homeostasis may be maintained in leaves through diversion of intermediates into glycoalkaloid biosynthesis, whereas in tuber flesh, excess intermediates are catalyzed by tuber-specificStLAS-like, resulting in low tuber glycoalkaloids.Lanosterol synthase (LAS) and cycloartenol synthase (CAS) are phylogenetically related enzymes. Cycloartenol is the accepted precursor leading to cholesterol and phytosterols, and in potato, to steroidal glycoalkaloid (SGA) biosynthesis… CONTINUE READING

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