Langerhans cells are required for efficient presentation of topically applied hapten to T cells.

@article{Bennett2007LangerhansCA,
  title={Langerhans cells are required for efficient presentation of topically applied hapten to T cells.},
  author={Clare Bennett and Madelon Noordegraaf and Cerithsa A. E. Martina and Bj{\"o}rn E Clausen},
  journal={Journal of immunology},
  year={2007},
  volume={179 10},
  pages={6830-5}
}
Dendritic cells (DC) play a pivotal role in the control of T cell immunity due to their ability to stimulate naive T cells and direct effector function. Murine and human DC are composed of a number of phenotypically, and probably developmentally, distinct subsets, which may play unique roles in the initiation and regulation of T cell responses. The skin is populated by at least two subsets of DC: Langerhans cells (LC), which form a contiguous network throughout the epidermis, and dermal DC. LC… CONTINUE READING