Langerhans Cells Orchestrate TFH-Dependent Humoral Immunity.


T follicular helper cells contribute to the development of long-lasting humoral immunity by germinal center formation. Somatic hypermutation and affinity maturation take place in germinal centers leading to the generation of memory B cells and plasma cells. As such, T follicular helper cells impact immunodeficiencies, autoimmunity, and cancer. This… (More)
DOI: 10.1016/j.jid.2017.06.014