Langerhans' cell histiocytosis of the head and neck in children.

  title={Langerhans' cell histiocytosis of the head and neck in children.},
  author={Simon I. Angeli and Juan Pablo de la Plata Alcalde and Henry T Hoffman and Richard J H Smith},
  journal={The Annals of otology, rhinology, and laryngology},
  volume={104 3},
This is a retrospective analysis of a 29-year institutional experience with Langerhans' cell histiocytosis (LCH) in children. Cases of LCH were categorized by disease extent into three groups: group 1, with a solitary focus of LCH; group 2, with multiple non-vital organ foci; and group 3, with vital organ disease. Sixteen patients averaging 7.3 years of age and with 11.0 years of follow-up presented in group 1. One child experienced a spontaneous remission; all other children responded to local… CONTINUE READING