Landscape of somatic mutations in gastric cancer assessed using next-generation sequencing analysis

@article{Pan2018LandscapeOS,
  title={Landscape of somatic mutations in gastric cancer assessed using next-generation sequencing analysis},
  author={Xuan Pan and Xiaozhi Ji and Renmin Zhang and Zhaofei Zhou and Yuejiao Zhong and Wei Peng and Ning Sun and Xinyu Xu and Lei Xia and Pansong Li and Jianwei Lu and Jing Tu},
  journal={Oncology Letters},
  year={2018},
  volume={16},
  pages={4863 - 4870}
}
Gastric cancer is a highly heterogeneous disease and the second leading cause of cancer-associated mortality. However, the genomic basis of gastric cancer is not completely understood and the underlying genetic heterogeneity has not been well studied. In the present study, 1,021 genes were sequenced and the somatic mutations of 45 formalin-fixed, paraffin-embedded gastric adenocarcinoma samples were assessed using next-generation sequencing technologies. In the present study, a median… Expand
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