Laminin induces the expression of cytokeratin 19 in hepatocellular carcinoma cells growing in culture.

Abstract

AIM To study the abnormal cytokeratin (CK) expression, emergence of CK19 with or without CK7, in liver parenchymal cells and the role of laminin (LN), a basement membrane protein, in this process. METHODS Six hepatocellular carcinoma (HCC) cell lines were examined for different CKs, LN and its receptor by immunocytochemistry and Western blotting. Double… (More)

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