Laminin binding conveys mechanosensing in endothelial cells.

  title={Laminin binding conveys mechanosensing in endothelial cells.},
  author={Torsten Gloe and Ulrich Dipl Ing Pohl},
  journal={News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society},
  • T. GloeU. Pohl
  • Published 1 August 2002
  • Biology
  • News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
In endothelial cells, forces like shear stress are transferred to focal adhesion sites and activate in concert with matrix receptor kinases, leading to an initiation of signaling cascades. The laminin binding protein is one of these matrix receptors and is critically involved in sensing and quantification of shear stress. 

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