Laminin alpha3 LG4 module induces keratinocyte migration: involvement of matrix metalloproteinase-9.

@article{Momota2005LamininAL,
  title={Laminin alpha3 LG4 module induces keratinocyte migration: involvement of matrix metalloproteinase-9.},
  author={Yutaka Momota and Nobuharu Suzuki and Yoshitoshi Kasuya and Takashi Kobayashi and Masako Mizoguchi and Fumiharu Yokoyama and Motoyoshi Nomizu and Hiroshi Shinkai and Toshiroh Iwasaki and Atsushi Utani},
  journal={Journal of receptor and signal transduction research},
  year={2005},
  volume={25 1},
  pages={1-17}
}
Laminin alpha3 chain, a functionally key subunit of laminin-5, contains a large globular module (G module) which consists of a tandem repeat of five homologous LG modules (LG1-5). We previously demonstrated that the LG4 module of laminin alpha3 chain (alpha3 LG4) induces a matrix metalloproteinase-1 (MMP-1) expression through the interaction with syndecans leading to MAPK activation/IL-1beta expression signaling loop (Utani et al., J. Biol. Chem. 278, 34483-34490, 2003). Here, we show that a… CONTINUE READING

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