Laminin alpha 2 is a component of brain capillary basement membrane: reduced expression in dystrophic dy mice.

@article{Jucker1996LamininA2,
  title={Laminin alpha 2 is a component of brain capillary basement membrane: reduced expression in dystrophic dy mice.},
  author={Mathias Jucker and Miao Tian and Darrell D. Norton and Christopher M Sherman and John W. Kusiak},
  journal={Neuroscience},
  year={1996},
  volume={71 4},
  pages={1153-61}
}
In the present study we demonstrate low level expression of the laminin alpha 2 chain in brain and localize the alpha 2 protein to the capillary basement membrane. While in peripheral basement membranes the laminin alpha 1 and alpha 2 chains have an almost mutually exclusive distribution, the present results suggest both alpha 1 and alpha 2 in the cerebral capillary basement membrane. Towards elucidating the function of alpha 2 in brain, we have performed ultrastructural analysis of the… CONTINUE READING

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