Laminin-5 expression is independent of the injury and the microenvironment during reepithelialization of wounds.

@article{Kainulainen1998Laminin5EI,
  title={Laminin-5 expression is independent of the injury and the microenvironment during reepithelialization of wounds.},
  author={Tiina J Kainulainen and L. V. T. Hakkinen and Sanaz Hamidi and Kari T. Larjava and Matti Kallioinen and Juha M. Peltonen and Timothy J. Salo and Hannu S Larjava and Aarne Oikarinen},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1998},
  volume={46 3},
  pages={
          353-60
        }
}
We examined the expression of laminin-5 and its integrin receptors during reepithelialization of human wounds. We used suction blisters of skin as a model of keratinocyte migration on a basement membrane matrix and mucosal full-thickness wounds as a model in which keratinocytes migrate in a provisional matrix. An animal model, in which human epidermal keratinocytes were injected into the back of athymic mice, was used to follow the deposition of the basement membrane components. In 4-day-old… CONTINUE READING
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