Laminar organization of spinal dorsal horn neurones activated by C- vs. A-heat nociceptors and their descending control from the periaqueductal grey in the rat

@article{Koutsikou2007LaminarOO,
  title={Laminar organization of spinal dorsal horn neurones activated by C- vs. A-heat nociceptors and their descending control from the periaqueductal grey in the rat},
  author={Stella Koutsikou and Dilys M. Parry and F M Macmillan and Bridget M Lumb},
  journal={The European Journal of Neuroscience},
  year={2007},
  volume={26},
  pages={943 - 952}
}
The periaqueductal grey can differentially control A- vs. C-nociceptor-evoked spinal reflexes and deep spinal dorsal horn neuronal responses. However, little is known about the control of A- vs. C-fibre inputs to lamina I and the lateral spinal nucleus, and how this correlates with the control of deeper laminae. To address this, the laminar distributions of neurones expressing Fos-like immunoreactivity were determined following preferential activation of A- or C-heat nociceptors, using fast or… CONTINUE READING

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