Laminar flow cells for single-molecule studies of DNA-protein interactions


Microfluidic flow cells are used in single-molecule experiments, enabling measurements to be made with high spatial and temporal resolution. We discuss the fundamental processes affecting flow cell operation and describe the flow cells in use at present for studying the interaction of optically trapped or mechanically isolated, single DNA molecules with… (More)
DOI: 10.1038/nmeth.1217


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